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KMID : 0369820170470050453
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Jorunal of Korean Pharmaceutical Sciences
2017 Volume.47 No. 5 p.453 ~ p.460
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Physicochemical and surface properties of acrylic intraocular lenses and their clinical significance
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Jung Gyeong-Bok
Jin Kyung-Hyun
Park Hun-Kuk
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Abstract
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To analyze and compare several commercially available acrylic intraocular lenses (IOLs) with particular regard to their clinical significance, we examined the physicochemical and surface properties of four currently available acrylic IOLs using static water contact angle, atomic force microscopy (AFM), Raman spectroscopy, and differential scanning calorimetry (DSC) measurements. The hydrophobic acrylic IOLs, ZA9003, and MA60BM, had contact angles ranging from 77.9°?±?0.65° to 84.4°?±?0.09°. The contact angles in the hydrophilic acrylic (970C) and heparin-surface-modified (HSM) hydrophilic acrylic IOLs (BioVue) were 61.8°?±?0.45° and 69.7°?±?0.76°, respectively. The roughness of the IOL optic surface differed depending on the type of IOL (p?
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KEYWORD
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Intraocular lens (IOLs), Cataract surgery, Atomic force microscopy (AFM), Raman spectroscopy, Surface characteristics, Biocompatibility
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